Monday, August 22, 2011

Emedinews: Dr Good Dr Bad: A patient with normal LDL and high CRP wanted to know his risk of CAD.

Situation: A patient with normal LDL and high CRP wanted to know his risk of CAD.
Dr Bad: You are not at risk.
Dr Good: Get cardiac 64 CT test done
Lesson: Among asymptomatic individuals with normal LDL cholesterol levels and elevated high-sensitivity C-reactive protein measuring the burden of calcium in the coronary arteries with cardiac CT appears to stratify the risk of cardiovascular disease

 (Ref: Blaha M, et al. Associations between C-reactive protein, coronary artery calcium, and cardiovascular events: implications for the JUPITER population from MESA, a population-based cohort study. Lancet 2011;378:684-92).

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